Correlating confocal microscopy and atomic force indentation reveals metastatic cancer cells stiffen during invasion into collagen I matrices

Mechanical interactions between cells and their microenvironment dictate cell phenotype and behavior, calling for cell mechanics measurements in three-dimensional (3D) extracellular matrices (ECM). Here we describe a novel technique for quantitative mechanical characterization of soft, heterogeneous...

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Detalles Bibliográficos
Autores principales: Staunton, Jack R., Doss, Bryant L., Lindsay, Stuart, Ros, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728602/
https://www.ncbi.nlm.nih.gov/pubmed/26813872
http://dx.doi.org/10.1038/srep19686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728602/
https://www.ncbi.nlm.nih.gov/pubmed/26813872
http://dx.doi.org/10.1038/srep19686

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