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Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer

Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria. BNIP3 and NIX are critical mediators for the Mieap-regulated mitochondrial quality control. Mieap suppresses murine intestinal tumor via its mitochondrial quality control function. To e...

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Detalles Bibliográficos
Autores principales: Kamino, H, Nakamura, Y, Tsuneki, M, Sano, H, Miyamoto, Y, Kitamura, N, Futamura, M, Kanai, Y, Taniguchi, H, Shida, D, Kanemitsu, Y, Moriya, Y, Yoshida, K, Arakawa, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728673/
https://www.ncbi.nlm.nih.gov/pubmed/26727575
http://dx.doi.org/10.1038/oncsis.2015.43