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Energy disruptors: rising stars in anticancer therapy?

The metabolic features of tumor cells diverge from those of normal cells. Otto Warburg was the first to observe that cancer cells dramatically increase their glucose consumption to generate ATP. He also claimed that cancer cells do not have functional mitochondria or oxidative phosphorylation (OXPHO...

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Detalles Bibliográficos
Autores principales: Bost, F, Decoux-Poullot, A-G, Tanti, J F, Clavel, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728676/
https://www.ncbi.nlm.nih.gov/pubmed/26779810
http://dx.doi.org/10.1038/oncsis.2015.46