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Chromosomal copy number analysis on chorionic villus samples from early spontaneous miscarriages by high throughput genetic technology

BACKGROUND: About 10 –15 % of all clinically recognized pregnancies result in spontaneous miscarriages, and chromosomal abnormalities are the most common reason. The conventional karyotyping on chorionic villus samples (CVSs) is limited by cell culture and its resolution. This study aimed at evaluat...

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Detalles Bibliográficos
Autores principales: Shen, Jiandong, Wu, Wei, Gao, Chao, Ochin, Humphrey, Qu, Dianyun, Xie, Jiazi, Gao, Li, Zhou, Yadong, Cui, Yugui, Liu, Jiayin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728779/
https://www.ncbi.nlm.nih.gov/pubmed/26819630
http://dx.doi.org/10.1186/s13039-015-0210-z