Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism

BACKGROUND: A reduction of the number of parvalbumin (PV)-immunoreactive (PV(+)) GABAergic interneurons or a decrease in PV immunoreactivity was reported in several mouse models of autism spectrum disorders (ASD). This includes Shank mutant mice, with SHANK being one of the most important gene famil...

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Detalles Bibliográficos
Autores principales: Filice, Federica, Vörckel, Karl Jakob, Sungur, Ayse Özge, Wöhr, Markus, Schwaller, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729132/
https://www.ncbi.nlm.nih.gov/pubmed/26819149
http://dx.doi.org/10.1186/s13041-016-0192-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729132/
https://www.ncbi.nlm.nih.gov/pubmed/26819149
http://dx.doi.org/10.1186/s13041-016-0192-8

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