Isoform prefiltering improves performance of count-based methods for analysis of differential transcript usage

BACKGROUND: RNA-seq has been a boon to the quantitative analysis of transcriptomes. A notable application is the detection of changes in transcript usage between experimental conditions. For example, discovery of pathological alternative splicing may allow the development of new treatments or better...

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Detalles Bibliográficos
Autores principales: Soneson, Charlotte, Matthes, Katarina L., Nowicka, Malgorzata, Law, Charity W., Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729156/
https://www.ncbi.nlm.nih.gov/pubmed/26813113
http://dx.doi.org/10.1186/s13059-015-0862-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729156/
https://www.ncbi.nlm.nih.gov/pubmed/26813113
http://dx.doi.org/10.1186/s13059-015-0862-3

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