Simultaneous Determination and Pharmacokinetic Study of Losartan, Losartan Carboxylic Acid, Ramipril, Ramiprilat, and Hydrochlorothiazide in Rat Plasma by a Liquid Chromatography/Tandem Mass Spectrometry Method

The monitoring of the plasmatic concentrations of cardiovascular drugs is crucial for understanding their pharmacokinetics and pharmacodynamics. A simple, sensitive, specific, and high-throughput liquid chromatography/tandem mass spectrometry (LC–MS/MS) method was developed and validated for the sim...

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Detalles Bibliográficos
Autores principales: Dubey, Ramkumar, Ghosh, Manik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Austrian Journal of Pharmaceutical Sciences 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729183/
https://www.ncbi.nlm.nih.gov/pubmed/26839805
http://dx.doi.org/10.3797/scipharm.1410-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729183/
https://www.ncbi.nlm.nih.gov/pubmed/26839805
http://dx.doi.org/10.3797/scipharm.1410-15

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