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Manufacturing of AcMNPV baculovirus vectors to enable gene therapy trials

Over the past two decades, baculoviruses have become workhorse research tools for transient transgene expression. Although they have not yet been used directly as a gene therapy vector in the clinical setting, numerous preclinical studies have suggested the highly promising potential of baculovirus...

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Detalles Bibliográficos
Autores principales: Kwang, Timothy Weixin, Zeng, Xinhui, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729316/
https://www.ncbi.nlm.nih.gov/pubmed/26858963
http://dx.doi.org/10.1038/mtm.2015.50