Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis

Transgenic expression of antigen-specific T-cell receptor (TCR) genes is a promising approach for immunotherapy against infectious diseases and cancers. A key to the efficient application of this approach is the rapid and specific isolation and cloning of TCRs. Current methods are often labor-intens...

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Detalles Bibliográficos
Autores principales: Guo, Xi-zhi J, Dash, Pradyot, Calverley, Matthew, Tomchuck, Suzanne, Dallas, Mari H, Thomas, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729322/
https://www.ncbi.nlm.nih.gov/pubmed/26858965
http://dx.doi.org/10.1038/mtm.2015.54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729322/
https://www.ncbi.nlm.nih.gov/pubmed/26858965
http://dx.doi.org/10.1038/mtm.2015.54

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