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Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation

Hundreds of double homeobox (DUX) genes map within 3.3-kb repeated elements dispersed in the human genome and encode DNA-binding proteins. Among these, we identified DUX4, a potent transcription factor that causes facioscapulohumeral muscular dystrophy (FSHD). In the present study, we performed yeas...

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Detalles Bibliográficos
Autores principales: Ansseau, Eugénie, Eidahl, Jocelyn O., Lancelot, Céline, Tassin, Alexandra, Matteotti, Christel, Yip, Cassandre, Liu, Jian, Leroy, Baptiste, Hubeau, Céline, Gerbaux, Cécile, Cloet, Samuel, Wauters, Armelle, Zorbo, Sabrina, Meyer, Pierre, Pirson, Isabelle, Laoudj-Chenivesse, Dalila, Wattiez, Ruddy, Harper, Scott Q., Belayew, Alexandra, Coppée, Frédérique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729438/
https://www.ncbi.nlm.nih.gov/pubmed/26816005
http://dx.doi.org/10.1371/journal.pone.0146893