The Amyloid Precursor Protein of Alzheimer’s Disease Clusters at the Organelle/Microtubule Interface on Organelles that Bind Microtubules in an ATP Dependent Manner

The amyloid precursor protein (APP) is a causal agent in the pathogenesis of Alzheimer’s disease and is a transmembrane protein that associates with membrane-limited organelles. APP has been shown to co-purify through immunoprecipitation with a kinesin light chain suggesting that APP may act as a tr...

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Detalles Bibliográficos
Autores principales: Stevenson, James W., Conaty, Eliza A., Walsh, Rylie B., Poidomani, Paul J., Samoriski, Colin M., Scollins, Brianne J., DeGiorgis, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729464/
https://www.ncbi.nlm.nih.gov/pubmed/26814888
http://dx.doi.org/10.1371/journal.pone.0147808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729464/
https://www.ncbi.nlm.nih.gov/pubmed/26814888
http://dx.doi.org/10.1371/journal.pone.0147808

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