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The Defect in Autophagy Induction by Clinical Isolates of Mycobacterium Tuberculosis Is Correlated with Poor Tuberculosis Outcomes

BACKGROUND: Tuberculosis (TB) represents a major global health problem. The prognosis of clinically active tuberculosis depends on the complex interactions between Mycobacterium tuberculosis (Mtb) and its host. In recent years, autophagy receives particular attention for its role in host defense aga...

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Detalles Bibliográficos
Autores principales: Li, Furong, Gao, Bo, Xu, Wei, Chen, Ling, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729487/
https://www.ncbi.nlm.nih.gov/pubmed/26815035
http://dx.doi.org/10.1371/journal.pone.0147810