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Genetic Polymorphism of CYP2D6 and Clomiphene Concentrations in Infertile Patients with Ovulatory Dysfunction Treated with Clomiphene Citrate

CYP2D6 is primarily responsible for the metabolism of clomiphene citrate (CC). The purpose of the present study was to investigate the relationship between CYP2D6 genotypes, concentrations of CC and its major metabolites and drug response in infertility patients. We studied 42 patients with ovulator...

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Detalles Bibliográficos
Autores principales: Ji, Misuk, Kim, Kwang-Rae, Lee, Woochang, Choe, Wonho, Chun, Sail, Min, Won-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729514/
https://www.ncbi.nlm.nih.gov/pubmed/26839488
http://dx.doi.org/10.3346/jkms.2016.31.2.310