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Lack of α(2C)-Adrenoceptor Results in Contrasting Phenotypes of Long Bones and Vertebra and Prevents the Thyrotoxicosis-Induced Osteopenia

A series of studies have demonstrated that activation of the sympathetic nervous system (SNS) causes osteopenia via β(2)-adrenoceptor (β(2)-AR) signaling. However, in a recent study, we found an unexpected and generalized phenotype of high bone mass in female mice with chronic sympathetic hyperactiv...

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Detalles Bibliográficos
Autores principales: Cruz Grecco Teixeira, Marilia Bianca, Martins, Gisele Miyamura, Miranda-Rodrigues, Manuela, De Araújo, Iasmin Ferreira, Oliveira, Ricardo, Brum, Patrícia Chakur, Azevedo Gouveia, Cecilia Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729682/
https://www.ncbi.nlm.nih.gov/pubmed/26815679
http://dx.doi.org/10.1371/journal.pone.0146795