Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development

Early mouse development is accompanied by dynamic changes in chromatin modifications, including G9a-mediated histone H3 lysine 9 dimethylation (H3K9me2), which is essential for embryonic development. Here we show that genome-wide accumulation of H3K9me2 is crucial for postimplantation development, a...

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Detalles Bibliográficos
Autores principales: Zylicz, Jan J, Dietmann, Sabine, Günesdogan, Ufuk, Hackett, Jamie A, Cougot, Delphine, Lee, Caroline, Surani, M Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729692/
https://www.ncbi.nlm.nih.gov/pubmed/26551560
http://dx.doi.org/10.7554/eLife.09571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729692/
https://www.ncbi.nlm.nih.gov/pubmed/26551560
http://dx.doi.org/10.7554/eLife.09571

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