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Effect of STAT3 inhibitor in chronic myeloid leukemia associated signaling pathway: a mathematical modeling, simulation and systems biology study

Chronic myeloid leukemia (CML) is a hematopoietic stem-cell disorder which proliferates due to abnormal growth of basophil cells. Several proangiogenic molecules have been reported to be associated in CML progression, including the hepatocyte growth factor (HGF). However, detail mechanism about the...

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Detalles Bibliográficos
Autores principales: Kumar, Himansu, Tichkule, Swapnil, Raj, Utkarsh, Gupta, Saurabh, Srivastava, Swati, Varadwaj, Pritish Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729759/
https://www.ncbi.nlm.nih.gov/pubmed/28330111
http://dx.doi.org/10.1007/s13205-015-0357-7