Mono-arginine Cholesterol-based Small Lipid Nanoparticles as a Systemic siRNA Delivery Platform for Effective Cancer Therapy

Although efforts have been made to develop a platform carrier for the delivery of RNAi therapeutics, systemic delivery of siRNA has shown only limited success in cancer therapy. Cationic lipid-based nanoparticles have been widely used for this purpose, but their toxicity and undesired liver uptake a...

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Detalles Bibliográficos
Autores principales: Lee, Jinju, Saw, Phei Er, Gujrati, Vipul, Lee, Yonghyun, Kim, Hyungjun, Kang, Sukmo, Choi, Minsuk, Kim, Jae-Il, Jon, Sangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729768/
https://www.ncbi.nlm.nih.gov/pubmed/26877778
http://dx.doi.org/10.7150/thno.13657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729768/
https://www.ncbi.nlm.nih.gov/pubmed/26877778
http://dx.doi.org/10.7150/thno.13657

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