Cardiac expression of the CREM repressor isoform CREM-IbΔC-X in mice leads to arrhythmogenic alterations in ventricular cardiomyocytes

Chronic β-adrenergic stimulation is regarded as a pivotal step in the progression of heart failure which is associated with a high risk for arrhythmia. The cAMP-dependent transcription factors cAMP-responsive element binding protein (CREB) and cAMP-responsive element modulator (CREM) mediate transcr...

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Detalles Bibliográficos
Autores principales: Schulte, J. S., Fehrmann, E., Tekook, M. A., Kranick, D., Fels, B., Li, N., Wehrens, X. H. T., Heinick, A., Seidl, M. D., Schmitz, W., Müller, F. U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729809/
https://www.ncbi.nlm.nih.gov/pubmed/26818679
http://dx.doi.org/10.1007/s00395-016-0532-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729809/
https://www.ncbi.nlm.nih.gov/pubmed/26818679
http://dx.doi.org/10.1007/s00395-016-0532-y

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