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Human pancreatic beta-like cells converted from fibroblasts

Pancreatic beta cells are of great interest for biomedical research and regenerative medicine. Here we show the conversion of human fibroblasts towards an endodermal cell fate by employing non-integrative episomal reprogramming factors in combination with specific growth factors and chemical compoun...

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Detalles Bibliográficos
Autores principales: Zhu, Saiyong, Russ, Holger A., Wang, Xiaojing, Zhang, Mingliang, Ma, Tianhua, Xu, Tao, Tang, Shibing, Hebrok, Matthias, Ding, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729817/
https://www.ncbi.nlm.nih.gov/pubmed/26733021
http://dx.doi.org/10.1038/ncomms10080