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Human pancreatic beta-like cells converted from fibroblasts
Pancreatic beta cells are of great interest for biomedical research and regenerative medicine. Here we show the conversion of human fibroblasts towards an endodermal cell fate by employing non-integrative episomal reprogramming factors in combination with specific growth factors and chemical compoun...
Autores principales: | Zhu, Saiyong, Russ, Holger A., Wang, Xiaojing, Zhang, Mingliang, Ma, Tianhua, Xu, Tao, Tang, Shibing, Hebrok, Matthias, Ding, Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729817/ https://www.ncbi.nlm.nih.gov/pubmed/26733021 http://dx.doi.org/10.1038/ncomms10080 |
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