Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability

The life-long maintenance of haematopoietic stem and progenitor cells (HSPCs) critically relies on environmental signals produced by cells that constitute the haematopoietic niche. Here we report a cell-intrinsic mechanism whereby haematopoietic cells limit proliferation within the bone marrow, and...

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Detalles Bibliográficos
Autores principales: Leiva, Magdalena, Quintana, Juan A., Ligos, José M., Hidalgo, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729861/
https://www.ncbi.nlm.nih.gov/pubmed/26742601
http://dx.doi.org/10.1038/ncomms10222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729861/
https://www.ncbi.nlm.nih.gov/pubmed/26742601
http://dx.doi.org/10.1038/ncomms10222

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