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Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Signaling Networks Against Human Colon Cancer Cells

The aim of this study was to evaluate the cytotoxic potential of a novel nickel(II) complex (NTC) against WiDr and HT-29 human colon cancer cells by determining the IC(50) using the standard MTT assay. The NTC displayed a strong suppressive effect on colon cancer cells with an IC(50) value of 6.07 ±...

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Detalles Bibliográficos
Autores principales: Samie, Nima, Haerian, Batoul Sadat, Muniandy, Sekaran, Marlina, Anita, Kanthimathi, M. S., Abdullah, Norbani B., Ahmadian, Gholamreza, Aziddin, Raja E. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729910/
https://www.ncbi.nlm.nih.gov/pubmed/26858642
http://dx.doi.org/10.3389/fphar.2015.00313