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Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress

Anaplastic large cell lymphoma (ALCL) is a peripheral T-cell lymphoma presenting mostly in children and young adults. The natural progression of this disease is largely unknown as is the identity of its true cell of origin. Here we present a model of peripheral ALCL pathogenesis where the malignancy...

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Detalles Bibliográficos
Autores principales: Malcolm, Tim I. M., Villarese, Patrick, Fairbairn, Camilla J., Lamant, Laurence, Trinquand, Amélie, Hook, C. Elizabeth, Burke, G. A. Amos, Brugières, Laurence, Hughes, Katherine, Payet, Dominique, Merkel, Olaf, Schiefer, Ana-Iris, Ashankyty, Ibraheem, Mian, Shahid, Wasik, Mariusz, Turner, Martin, Kenner, Lukas, Asnafi, Vahid, Macintyre, Elizabeth, Turner, Suzanne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729925/
https://www.ncbi.nlm.nih.gov/pubmed/26753883
http://dx.doi.org/10.1038/ncomms10087