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Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus

Timely generation and normal maturation of ependymal cells along the aqueduct are critical for preventing physical blockage between the third and fourth ventricles and the development of fetal non-communicating hydrocephalus. Our study identifies Yap, the downstream effector of the evolutionarily co...

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Detalles Bibliográficos
Autores principales: Park, Raehee, Moon, Uk Yeol, Park, Jun Young, Hughes, Lucinda J., Johnson, Randy L., Cho, Seo-Hee, Kim, Seonhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729961/
https://www.ncbi.nlm.nih.gov/pubmed/26754915
http://dx.doi.org/10.1038/ncomms10329