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An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels

Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias, cancer and trauma. To explore the mechanism by which Ca(2+) blocks intercellular communication during tissue injury, we determined the X-ray cr...

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Detalles Bibliográficos
Autores principales: Bennett, Brad C., Purdy, Michael D., Baker, Kent A., Acharya, Chayan, McIntire, William E., Stevens, Raymond C., Zhang, Qinghai, Harris, Andrew L., Abagyan, Ruben, Yeager, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730032/
https://www.ncbi.nlm.nih.gov/pubmed/26753910
http://dx.doi.org/10.1038/ncomms9770