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An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels
Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias, cancer and trauma. To explore the mechanism by which Ca(2+) blocks intercellular communication during tissue injury, we determined the X-ray cr...
Autores principales: | Bennett, Brad C., Purdy, Michael D., Baker, Kent A., Acharya, Chayan, McIntire, William E., Stevens, Raymond C., Zhang, Qinghai, Harris, Andrew L., Abagyan, Ruben, Yeager, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730032/ https://www.ncbi.nlm.nih.gov/pubmed/26753910 http://dx.doi.org/10.1038/ncomms9770 |
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