Reversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal Transitions

Epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) are observed during both physiological liver wound healing and the pathological fibrotic/carcinogenic (fibro-carcinogenetic) process. TGF-β and pro-inflammatory cytokine are considered to be the major factors acceler...

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Detalles Bibliográficos
Autores principales: Yoshida, Katsunori, Murata, Miki, Yamaguchi, Takashi, Matsuzaki, Koichi, Okazaki, Kazuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730132/
https://www.ncbi.nlm.nih.gov/pubmed/26771649
http://dx.doi.org/10.3390/jcm5010007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730132/
https://www.ncbi.nlm.nih.gov/pubmed/26771649
http://dx.doi.org/10.3390/jcm5010007

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