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Recombinant pre-miR-29b for Alzheimer´s disease therapeutics

MicroRNAs are arising as the next generation of diagnostic and therapeutic tools for gene silencing. Studies demonstrated that the miR-29 expression is decreased in Alzheimer’s disease (AD) patients displaying high levels of human β-secretase (hBACE1). Recent advances toward an effective therapy for...

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Detalles Bibliográficos
Autores principales: Pereira, Patrícia A., Tomás, Joana F., Queiroz, João A., Figueiras, Ana R., Sousa, Fani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730146/
https://www.ncbi.nlm.nih.gov/pubmed/26818210
http://dx.doi.org/10.1038/srep19946