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Recombinant pre-miR-29b for Alzheimer´s disease therapeutics
MicroRNAs are arising as the next generation of diagnostic and therapeutic tools for gene silencing. Studies demonstrated that the miR-29 expression is decreased in Alzheimer’s disease (AD) patients displaying high levels of human β-secretase (hBACE1). Recent advances toward an effective therapy for...
Autores principales: | Pereira, Patrícia A., Tomás, Joana F., Queiroz, João A., Figueiras, Ana R., Sousa, Fani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730146/ https://www.ncbi.nlm.nih.gov/pubmed/26818210 http://dx.doi.org/10.1038/srep19946 |
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