Topical imiquimod yields systemic effects due to unintended oral uptake

Repetitive application of topical imiquimod is used as an experimental model for the induction of psoriasiform skin lesions in mice. The model is characterized by several inflammatory processes, including cytokine production both locally and systemically, cellular infiltration, and splenomegaly. To...

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Detalles Bibliográficos
Autores principales: Grine, Lynda, Steeland, Sophie, Van Ryckeghem, Sara, Ballegeer, Marlies, Lienenklaus, Stefan, Weiss, Siegfried, Sanders, Niek N., Vandenbroucke, Roosmarijn E., Libert, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730190/
https://www.ncbi.nlm.nih.gov/pubmed/26818707
http://dx.doi.org/10.1038/srep20134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730190/
https://www.ncbi.nlm.nih.gov/pubmed/26818707
http://dx.doi.org/10.1038/srep20134

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