Cargando…

The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors

LysR Type Transcriptional Regulators (LTTRs) regulate basic metabolic pathways or virulence gene expression in prokaryotes. Evidence suggests that the activation of LTTRs involves a conformational change from an inactive compact apo- configuration that represses transcription to an active, expanded...

Descripción completa

Detalles Bibliográficos
Autores principales: Lerche, Michael, Dian, Cyril, Round, Adam, Lönneborg, Rosa, Brzezinski, Peter, Leonard, Gordon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730206/
https://www.ncbi.nlm.nih.gov/pubmed/26817994
http://dx.doi.org/10.1038/srep19988