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The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors
LysR Type Transcriptional Regulators (LTTRs) regulate basic metabolic pathways or virulence gene expression in prokaryotes. Evidence suggests that the activation of LTTRs involves a conformational change from an inactive compact apo- configuration that represses transcription to an active, expanded...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730206/ https://www.ncbi.nlm.nih.gov/pubmed/26817994 http://dx.doi.org/10.1038/srep19988 |