Adenylylation of Tyr77 stabilizes Rab1b GTPase in an active state: A molecular dynamics simulation analysis

The pathogenic pathway of Legionella pneumophila exploits the intercellular vesicle transport system via the posttranslational attachment of adenosine monophosphate (AMP) to the Tyr77 sidechain of human Ras like GTPase Rab1b. The modification, termed adenylylation, is performed by the bacterial enzy...

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Detalles Bibliográficos
Autores principales: Luitz, Manuel P., Bomblies, Rainer, Ramcke, Evelyn, Itzen, Aymelt, Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730224/
https://www.ncbi.nlm.nih.gov/pubmed/26818796
http://dx.doi.org/10.1038/srep19896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730224/
https://www.ncbi.nlm.nih.gov/pubmed/26818796
http://dx.doi.org/10.1038/srep19896

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