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siRNAmod: A database of experimentally validated chemically modified siRNAs

Small interfering RNA (siRNA) technology has vast potential for functional genomics and development of therapeutics. However, it faces many obstacles predominantly instability of siRNAs due to nuclease digestion and subsequently biologically short half-life. Chemical modifications in siRNAs provide...

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Detalles Bibliográficos
Autores principales: Dar, Showkat Ahmad, Thakur, Anamika, Qureshi, Abid, Kumar, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730238/
https://www.ncbi.nlm.nih.gov/pubmed/26818131
http://dx.doi.org/10.1038/srep20031