Novel Insights into Guide RNA 5′-Nucleoside/Tide Binding by Human Argonaute 2

The human Argonaute 2 (hAgo2) protein is a key player of RNA interference (RNAi). Upon complex formation with small non-coding RNAs, the protein initially interacts with the 5′-end of a given guide RNA through multiple interactions within the MID domain. This interaction has been reported to show a...

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Detalles Bibliográficos
Autores principales: Kalia, Munishikha, Willkomm, Sarah, Claussen, Jens Christian, Restle, Tobias, Bonvin, Alexandre M. J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730269/
https://www.ncbi.nlm.nih.gov/pubmed/26712743
http://dx.doi.org/10.3390/ijms17010022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730269/
https://www.ncbi.nlm.nih.gov/pubmed/26712743
http://dx.doi.org/10.3390/ijms17010022

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