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Novel Insights into Guide RNA 5′-Nucleoside/Tide Binding by Human Argonaute 2
The human Argonaute 2 (hAgo2) protein is a key player of RNA interference (RNAi). Upon complex formation with small non-coding RNAs, the protein initially interacts with the 5′-end of a given guide RNA through multiple interactions within the MID domain. This interaction has been reported to show a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730269/ https://www.ncbi.nlm.nih.gov/pubmed/26712743 http://dx.doi.org/10.3390/ijms17010022 |