Aire-Overexpressing Dendritic Cells Induce Peripheral CD4(+) T Cell Tolerance

Autoimmune regulator (Aire) can promote the ectopic expression of peripheral tissue-restricted antigens (TRAs) in thymic medullary epithelial cells (mTECs), which leads to the deletion of autoreactive T cells and consequently prevents autoimmune diseases. However, the functions of Aire in the periph...

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Detalles Bibliográficos
Autores principales: Li, Dongbei, Li, Haijun, Fu, Haiying, Niu, Kunwei, Guo, Yantong, Guo, Chuan, Sun, Jitong, Li, Yi, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730283/
https://www.ncbi.nlm.nih.gov/pubmed/26729097
http://dx.doi.org/10.3390/ijms17010038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730283/
https://www.ncbi.nlm.nih.gov/pubmed/26729097
http://dx.doi.org/10.3390/ijms17010038

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