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Aire-Overexpressing Dendritic Cells Induce Peripheral CD4(+) T Cell Tolerance

Autoimmune regulator (Aire) can promote the ectopic expression of peripheral tissue-restricted antigens (TRAs) in thymic medullary epithelial cells (mTECs), which leads to the deletion of autoreactive T cells and consequently prevents autoimmune diseases. However, the functions of Aire in the periph...

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Detalles Bibliográficos
Autores principales:	Li, Dongbei, Li, Haijun, Fu, Haiying, Niu, Kunwei, Guo, Yantong, Guo, Chuan, Sun, Jitong, Li, Yi, Yang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730283/ https://www.ncbi.nlm.nih.gov/pubmed/26729097 http://dx.doi.org/10.3390/ijms17010038

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