Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells

Colorectal cancer (CRC) is one of the most common malignancies worldwide with substantial mortality and morbidity. Alisertib (ALS) is a selective Aurora kinase A (AURKA) inhibitor with unclear effect and molecular interactome on CRC. This study aimed to evaluate the molecular interactome and antican...

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Detalles Bibliográficos
Autores principales: Ren, Bao-Jun, Zhou, Zhi-Wei, Zhu, Da-Jian, Ju, Yong-Le, Wu, Jin-Hao, Ouyang, Man-Zhao, Chen, Xiao-Wu, Zhou, Shu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730286/
https://www.ncbi.nlm.nih.gov/pubmed/26729093
http://dx.doi.org/10.3390/ijms17010041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730286/
https://www.ncbi.nlm.nih.gov/pubmed/26729093
http://dx.doi.org/10.3390/ijms17010041

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