The Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate Response

The interferon (IFN)-regulated endoribonuclease RNase-L is involved in multiple aspects of the antimicrobial innate immune response. It is the terminal component of an RNA cleavage pathway in which dsRNA induces the production of RNase-L-activating 2-5A by the 2′-5′-oligoadenylate synthetase. The ac...

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Detalles Bibliográficos
Autores principales: Ezelle, Heather J., Malathi, Krishnamurthy, Hassel, Bret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730318/
https://www.ncbi.nlm.nih.gov/pubmed/26760998
http://dx.doi.org/10.3390/ijms17010074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730318/
https://www.ncbi.nlm.nih.gov/pubmed/26760998
http://dx.doi.org/10.3390/ijms17010074

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