Genipin Derivatives Protect RGC-5 from Sodium Nitroprusside-Induced Nitrosative Stress

CHR20 and CHR21 are a pair of stable diastereoisomers derived from genipin. These stereoisomers are activators of neuronal nitric oxide synthase (nNOS) and endothelial nitric oxide synthase (eNOS). In the rat retinal ganglion (RGC-5) cell model these compounds are non-toxic. Treatment of RGC-5 with...

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Detalles Bibliográficos
Autores principales: Wang, Rikang, Zhao, Jiaqiang, Zhang, Lei, Peng, Lizhi, Zhang, Xinyi, Zheng, Wenhua, Chen, Heru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730358/
https://www.ncbi.nlm.nih.gov/pubmed/26797604
http://dx.doi.org/10.3390/ijms17010117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730358/
https://www.ncbi.nlm.nih.gov/pubmed/26797604
http://dx.doi.org/10.3390/ijms17010117

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