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The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation

BACKGROUND: Gender, genetic makeup, and prior experience interact to determine physiological responses to an external perceived stressor. Here, we investigated the contribution of both genetic variants and promoter methylation of the NR3C1 (glucocorticoid receptor) gene to the cardiovascular and hyp...

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Detalles Bibliográficos
Autores principales: Li-Tempel, Ting, Larra, Mauro F., Sandt, Estelle, Mériaux, Sophie B., Schote, Andrea B., Schächinger, Hartmut, Muller, Claude P., Turner, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730588/
https://www.ncbi.nlm.nih.gov/pubmed/26823689
http://dx.doi.org/10.1186/s13148-016-0180-y