A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone

BACKGROUND: Multimeric naphthoquinones are redox-active compounds that exhibit antineoplastic, antiprotozoal, and antiviral activities. Due to their multimodal effect on perturbation of cellular oxidative state, these compounds hold great potential as therapeutic agents against highly proliferative...

Descripción completa

Detalles Bibliográficos
Autores principales: Pidugu, Lakshmi Swarna Mukhi, Mbimba, J.C. Emmanuel, Ahmad, Muqeet, Pozharski, Edwin, Sausville, Edward A., Emadi, Ashkan, Toth, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730606/
https://www.ncbi.nlm.nih.gov/pubmed/26822308
http://dx.doi.org/10.1186/s12900-016-0052-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730606/
https://www.ncbi.nlm.nih.gov/pubmed/26822308
http://dx.doi.org/10.1186/s12900-016-0052-x

Ejemplares similares