DNA-binding sequence specificity of DUX4

BACKGROUND: Misexpression of the double homeodomain transcription factor DUX4 results in facioscapulohumeral muscular dystrophy (FSHD). A DNA-binding consensus with two tandem TAAT motifs based on chromatin IP peaks has been discovered; however, the consensus has multiple variations (flavors) of unk...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Lee, John K., Toso, Erik A., Lee, Joslynn S., Choi, Si Ho, Slattery, Matthew, Aihara, Hideki, Kyba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730607/
https://www.ncbi.nlm.nih.gov/pubmed/26823969
http://dx.doi.org/10.1186/s13395-016-0080-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730607/
https://www.ncbi.nlm.nih.gov/pubmed/26823969
http://dx.doi.org/10.1186/s13395-016-0080-z

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