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DNA-binding sequence specificity of DUX4
BACKGROUND: Misexpression of the double homeodomain transcription factor DUX4 results in facioscapulohumeral muscular dystrophy (FSHD). A DNA-binding consensus with two tandem TAAT motifs based on chromatin IP peaks has been discovered; however, the consensus has multiple variations (flavors) of unk...
Autores principales: | Zhang, Yu, Lee, John K., Toso, Erik A., Lee, Joslynn S., Choi, Si Ho, Slattery, Matthew, Aihara, Hideki, Kyba, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730607/ https://www.ncbi.nlm.nih.gov/pubmed/26823969 http://dx.doi.org/10.1186/s13395-016-0080-z |
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