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Evidence of a causal relationship between high serum adiponectin levels and increased cardiovascular mortality rate in patients with type 2 diabetes

BACKGROUND: Despite its beneficial role on insulin resistance and atherosclerosis, adiponectin has been repeatedly reported as an independent positive predictor of cardiovascular mortality. METHODS: A Mendelian randomization approach was used, in order to evaluate whether such counterintuitive assoc...

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Detalles Bibliográficos
Autores principales: Ortega Moreno, Lorena, Copetti, Massimiliano, Fontana, Andrea, De Bonis, Concetta, Salvemini, Lucia, Trischitta, Vincenzo, Menzaghi, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730617/
https://www.ncbi.nlm.nih.gov/pubmed/26817832
http://dx.doi.org/10.1186/s12933-016-0339-z