Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta

BACKGROUND: Alzheimer’s disease is associated with amyloid-beta (Aβ)-induced microglia activation. This pro-inflammatory response promotes neuronal damage, and therapies are sought to limit microglial activation. Screening efforts to develop new pharmacological inhibitors require a robust in vitro c...

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Detalles Bibliográficos
Autores principales: McCarthy, Ryan C., Lu, Dah-Yuu, Alkhateeb, Ahmed, Gardeck, Andrew M., Lee, Chih-Hao, Wessling-Resnick, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730646/
https://www.ncbi.nlm.nih.gov/pubmed/26819091
http://dx.doi.org/10.1186/s12974-016-0484-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730646/
https://www.ncbi.nlm.nih.gov/pubmed/26819091
http://dx.doi.org/10.1186/s12974-016-0484-z

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