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Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta

BACKGROUND: Alzheimer’s disease is associated with amyloid-beta (Aβ)-induced microglia activation. This pro-inflammatory response promotes neuronal damage, and therapies are sought to limit microglial activation. Screening efforts to develop new pharmacological inhibitors require a robust in vitro c...

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Detalles Bibliográficos
Autores principales:	McCarthy, Ryan C., Lu, Dah-Yuu, Alkhateeb, Ahmed, Gardeck, Andrew M., Lee, Chih-Hao, Wessling-Resnick, Marianne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730646/ https://www.ncbi.nlm.nih.gov/pubmed/26819091 http://dx.doi.org/10.1186/s12974-016-0484-z

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