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Obesity inhibits the osteogenic differentiation of human adipose-derived stem cells

BACKGROUND: Craniomaxillofacial defects secondary to trauma, tumor resection, or congenital malformations are frequent unmet challenges, due to suboptimal alloplastic options and limited autologous tissues such as bone. Significant advances have been made in the application of adipose-derived stem/s...

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Detalles Bibliográficos
Autores principales: Strong, Amy L., Hunter, Ryan S., Jones, Robert B., Bowles, Annie C., Dutreil, Maria F., Gaupp, Dina, Hayes, Daniel J., Gimble, Jeffrey M., Levi, Benjamin, McNulty, Margaret A., Bunnell, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730660/
https://www.ncbi.nlm.nih.gov/pubmed/26818763
http://dx.doi.org/10.1186/s12967-016-0776-1