Cargando…

High-fat diet impairs spatial memory and hippocampal intrinsic excitability and sex-dependently alters circulating insulin and hippocampal insulin sensitivity

BACKGROUND: High-fat diets promoting obesity/type-2 diabetes can impair physiology and cognitive performance, although sex-dependent comparisons of these impairments are rarely made. Transient reductions in Ca(2+)-dependent afterhyperpolarizations (AHPs) occur during memory consolidation, enhancing...

Descripción completa

Detalles Bibliográficos
Autores principales: Underwood, Erica L., Thompson, Lucien T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730722/
https://www.ncbi.nlm.nih.gov/pubmed/26823968
http://dx.doi.org/10.1186/s13293-016-0060-3